KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTN1
All Species:
35.15
Human Site:
T490
Identified Species:
96.67
UniProt:
P12814
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12814
NP_001093.1
892
103058
T490
W
D
N
L
G
A
L
T
Q
K
R
R
E
A
L
Chimpanzee
Pan troglodytes
XP_510027
892
103041
T490
W
D
N
L
G
A
L
T
Q
K
R
R
E
A
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_866874
892
102935
T490
W
D
N
L
G
A
L
T
Q
K
R
R
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPR4
892
103050
T490
W
D
N
L
G
A
L
T
Q
K
R
R
E
A
L
Rat
Rattus norvegicus
Q9Z1P2
892
102942
T490
W
D
N
L
G
A
L
T
Q
K
R
R
E
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P05094
893
103143
T491
W
D
N
L
G
A
L
T
Q
K
R
R
E
A
L
Frog
Xenopus laevis
NP_001084298
890
103039
T488
W
D
N
L
G
A
L
T
Q
K
R
R
D
A
L
Zebra Danio
Brachydanio rerio
NP_001161758
902
104186
T500
W
D
S
L
G
V
L
T
Q
K
R
S
E
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18091
924
107001
T522
W
D
R
L
G
A
L
T
Q
R
R
R
T
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
N.A.
99.3
N.A.
99.2
99.3
N.A.
N.A.
97.6
93.9
92.6
N.A.
67.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
N.A.
99.6
N.A.
99.4
99.5
N.A.
N.A.
98.5
97.1
95.7
N.A.
81.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
80
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
86.6
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
89
0
0
0
0
0
0
0
100
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% K
% Leu:
0
0
0
100
0
0
100
0
0
0
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
12
100
89
0
0
0
% R
% Ser:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _